Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress

Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress

The cJun NH2-terminal kinase (JNK) signaling pathway is implicated in the response to metabolic stress. Indeed, it is established that the ubiquitously expressed JNK1 and JNK2 isoforms regulate energy expenditure and insulin resistance. However, the role of the neuron-specific isoform JNK3 is unclea...

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Bibliographic Details
Main Authors: Vernia, Santiago, Morel, Caroline, Madara, Joseph C, Cavanagh-Kyros, Julie, Barrett, Tamera, Chase, Kathryn, Kennedy, Norman J, Jung, Dae Young, Kim, Jason K, Aronin, Neil, Flavell, Richard A, Lowell, Bradford B, Davis, Roger J
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798947/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798947/

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