Sample size calculations in clinical research should also be based on ethical principles
Sample size calculations based on too narrow a width, or with lower and upper confidence limits bounded by fixed cut-off points, not only increase power-based sample sizes to ethically unacceptable levels (thus making research practically unfeasible) but also greatly increase the costs and burdens o...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
BioMed Central
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797226/ |