Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation12

Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation12

The current paradigm of pancreatic neoplastic transformation proposes an initial step whereby acinar cells convert into acinar-to-ductal metaplasias, followed by progression of these lesions into neoplasias under sustained oncogenic activity and inflammation. Understanding the molecular mechanisms d...

Full description

Bibliographic Details
Main Authors: Drosos, Yiannis, Neale, Geoffrey, Ye, Jianming, Paul, Leena, Kuliyev, Emin, Maitra, Anirban, Means, Anna L, Washington, M Kay, Rehg, Jerold, Finkelstein, David B, Sosa-Pineda, Beatriz
Format: Online
Language:English
Published: Neoplasia Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796801/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796801/

Similar Items