Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice

Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice

Immune tolerance is executed partly by Foxp3+regulatory T (Treg) cells, which suppress autoreactive T cells. In autoimmune type 1 diabetes (T1D) impaired tolerance promotes destruction of insulin-producing β-cells. The development of autoantigen-specific vaccination strategies for Foxp3+Treg-inducti...

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Bibliographic Details
Main Authors: Serr, Isabelle, Fürst, Rainer W., Achenbach, Peter, Scherm, Martin G., Gökmen, Füsun, Haupt, Florian, Sedlmeier, Eva-Maria, Knopff, Annette, Shultz, Leonard, Willis, Richard A., Ziegler, Anette-Gabriele, Daniel, Carolin
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796321/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796321/

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