Sequence-dependent but not sequence-specific piRNA adhesion traps mRNAs to the germ plasm

The conserved Piwi family of proteins and piwi-interacting RNAs (piRNAs) play a central role in genomic stability, which is inextricably tied with germ cell formation, by forming ribonucleoproteins (piRNPs) that silence transposable elements (TEs)1. In Drosophila melanogaster and other animals, prim...

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Bibliographic Details
Main Authors: Vourekas, Anastassios, Alexiou, Panagiotis, Vrettos, Nicholas, Maragkakis, Manolis, Mourelatos, Zissimos
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795963/