Antitumor activity of pluripotent cell-engineered vaccines and their potential to treat lung cancer in relation to different levels of irradiation

Cancer stem cells (CSCs) are critical for tumor initiation/maintenance and recurrence or metastasis, so they may serve as a potential therapeutic target. However, CSC-established multitherapy resistance and immune tolerance render tumors resistant to current tumor-targeted strategies. To address thi...

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Bibliographic Details
Main Authors: Zhang, Yan-na, Duan, Xiao-gang, Zhang, Wen-hui, Wu, Ai-ling, Yang, Huan-Huan, Wu, Dong-ming, Wei, Yu-Quan, Chen, Xian-cheng
Format: Online
Language:English
Published: Dove Medical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795574/