Functionally different α-synuclein inclusions yield insight into Parkinson’s disease pathology

The formation of α-synuclein (α-S) amyloid aggregates, called Lewy bodies (LBs), is a hallmark of Parkinson’s disease (PD). The function of LBs in the disease process is however still unclear; they have been associated with both neuroprotection and toxicity. To obtain insight into this contradiction...

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Bibliographic Details
Main Authors: Raiss, Christian C., Braun, Theresa S., Konings, Irene B. M., Grabmayr, Heinrich, Hassink, Gerco C., Sidhu, Arshdeep, le Feber, Joost, Bausch, Andreas R., Jansen, Casper, Subramaniam, Vinod, Claessens, Mireille M. A. E.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794800/