Development of new fusion proteins for visualizing amyloid-β oligomers in vivo

Development of new fusion proteins for visualizing amyloid-β oligomers in vivo

The intracellular accumulation of amyloid-β (Aβ) oligomers critically contributes to disease progression in Alzheimer’s disease (AD) and can be the potential target of AD therapy. Direct observation of molecular dynamics of Aβ oligomers in vivo is key for drug discovery research, however, it has bee...

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Bibliographic Details
Main Authors: Ochiishi, Tomoyo, Doi, Motomichi, Yamasaki, Kazuhiko, Hirose, Keiko, Kitamura, Akira, Urabe, Takao, Hattori, Nobutaka, Kinjo, Masataka, Ebihara, Tatsuhiko, Shimura, Hideki
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793674/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793674/

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