Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains

Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains

TDP-43 is the major disease-associated protein involved in the pathogenesis and progression of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin-positive inclusions linked to TDP-43 pathology (FTLD-TDP). Abnormal phosphorylation, truncation and cytoplasmic mis-...

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Bibliographic Details
Main Authors: Kametani, Fuyuki, Obi, Tomokazu, Shishido, Takeo, Akatsu, Hiroyasu, Murayama, Shigeo, Saito, Yuko, Yoshida, Mari, Hasegawa, Masato
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793195/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793195/

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