IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease

IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease

The ability of CD4+ T cells to change their phenotype and to specialize into different functional subsets may enhance the risk of autoimmune diseases. Here we investigate how a pleiotropic cytokine interleukin (IL)-15 may modify the functional commitment of CD4+ T cells expressing the lineage-associ...

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Bibliographic Details
Main Authors: Tosiek, Milena J., Fiette, Laurence, El Daker, Sary, Eberl, Gérard, Freitas, Antonio A.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792960/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792960/

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