Immunodynamics: a cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials

The efficacy of PD-1/PD-L1 targeted therapies in addition to anti-CTLA-4 solidifies immunotherapy as a modality to add to the anticancer arsenal. Despite raising the bar of clinical efficacy, immunologically targeted agents raise new challenges to conventional drug development paradigms by highlight...

Full description

Bibliographic Details
Main Authors: Kohrt, Holbrook E., Tumeh, Paul C., Benson, Don, Bhardwaj, Nina, Brody, Joshua, Formenti, Silvia, Fox, Bernard A., Galon, Jerome, June, Carl H., Kalos, Michael, Kirsch, Ilan, Kleen, Thomas, Kroemer, Guido, Lanier, Lewis, Levy, Ron, Lyerly, H. Kim, Maecker, Holden, Marabelle, Aurelien, Melenhorst, Jos, Miller, Jeffrey, Melero, Ignacio, Odunsi, Kunle, Palucka, Karolina, Peoples, George, Ribas, Antoni, Robins, Harlan, Robinson, William, Serafini, Tito, Sondel, Paul, Vivier, Eric, Weber, Jeff, Wolchok, Jedd, Zitvogel, Laurence, Disis, Mary L., Cheever, Martin A.
Format: Online
Language:English
Published: BioMed Central 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791805/