Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State

The mitochondrial thioredoxin system (NADPH, thioredoxin reductase, thioredoxin) is a major redox regulator. Here we have investigated the redox correlation between this system and the mitochondrial enzyme cyclophilin D. The peptidyl prolyl cis-trans isomerase activity of cyclophilin D was stimulate...

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Bibliographic Details
Main Authors: Folda, Alessandra, Citta, Anna, Scalcon, Valeria, Calì, Tito, Zonta, Francesco, Scutari, Guido, Bindoli, Alberto, Rigobello, Maria Pia
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791683/