Gynura procumbens: An Overview of the Biological Activities

Gynura procumbens (Lour.) Merr. (Family Asteraceae) is a medicinal plant commonly found in tropical Asia countries such as China, Thailand, Indonesia, Malaysia, and Vietnam. Traditionally, it is widely used in many different countries for the treatment of a wide variety of health ailments such as ki...

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Main Authors: Tan, Hui-Li, Chan, Kok-Gan, Pusparajah, Priyia, Lee, Learn-Han, Goh, Bey-Hing
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791373/
id pubmed-4791373
recordtype oai_dc
spelling pubmed-47913732016-03-24 Gynura procumbens: An Overview of the Biological Activities Tan, Hui-Li Chan, Kok-Gan Pusparajah, Priyia Lee, Learn-Han Goh, Bey-Hing Pharmacology Gynura procumbens (Lour.) Merr. (Family Asteraceae) is a medicinal plant commonly found in tropical Asia countries such as China, Thailand, Indonesia, Malaysia, and Vietnam. Traditionally, it is widely used in many different countries for the treatment of a wide variety of health ailments such as kidney discomfort, rheumatism, diabetes mellitus, constipation, and hypertension. Based on the traditional uses of G. procumbens, it seems to possess high therapeutic potential for treatment of various diseases making it a target for pharmacological studies aiming to validate and provide scientific evidence for the traditional claims of its efficacy. Although there has been considerable progress in the research on G. procumbens, to date there is no review paper gathering the reported biological activities of G. procumbens. Hence, this review aims to provide an overview of the biological activities of G. procumbens based on reported in vitro and in vivo studies. In brief, G. procumbens has been reported to exhibit antihypertensive, cardioprotective, antihyperglycemic, fertility enhancement, anticancer, antimicrobial, antioxidant, organ protective, and antiinflammatory activity. The commercial applications of G. procumbens have also been summarized in this paper based on existing patents. The data compiled illustrate that G. procumbens is a potential natural source of compounds with various pharmacological actions which can be utilized for the development of novel therapeutic agents. Frontiers Media S.A. 2016-03-15 /pmc/articles/PMC4791373/ /pubmed/27014066 http://dx.doi.org/10.3389/fphar.2016.00052 Text en Copyright © 2016 Tan, Chan, Pusparajah, Lee and Goh. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Tan, Hui-Li
Chan, Kok-Gan
Pusparajah, Priyia
Lee, Learn-Han
Goh, Bey-Hing
spellingShingle Tan, Hui-Li
Chan, Kok-Gan
Pusparajah, Priyia
Lee, Learn-Han
Goh, Bey-Hing
Gynura procumbens: An Overview of the Biological Activities
author_facet Tan, Hui-Li
Chan, Kok-Gan
Pusparajah, Priyia
Lee, Learn-Han
Goh, Bey-Hing
author_sort Tan, Hui-Li
title Gynura procumbens: An Overview of the Biological Activities
title_short Gynura procumbens: An Overview of the Biological Activities
title_full Gynura procumbens: An Overview of the Biological Activities
title_fullStr Gynura procumbens: An Overview of the Biological Activities
title_full_unstemmed Gynura procumbens: An Overview of the Biological Activities
title_sort gynura procumbens: an overview of the biological activities
description Gynura procumbens (Lour.) Merr. (Family Asteraceae) is a medicinal plant commonly found in tropical Asia countries such as China, Thailand, Indonesia, Malaysia, and Vietnam. Traditionally, it is widely used in many different countries for the treatment of a wide variety of health ailments such as kidney discomfort, rheumatism, diabetes mellitus, constipation, and hypertension. Based on the traditional uses of G. procumbens, it seems to possess high therapeutic potential for treatment of various diseases making it a target for pharmacological studies aiming to validate and provide scientific evidence for the traditional claims of its efficacy. Although there has been considerable progress in the research on G. procumbens, to date there is no review paper gathering the reported biological activities of G. procumbens. Hence, this review aims to provide an overview of the biological activities of G. procumbens based on reported in vitro and in vivo studies. In brief, G. procumbens has been reported to exhibit antihypertensive, cardioprotective, antihyperglycemic, fertility enhancement, anticancer, antimicrobial, antioxidant, organ protective, and antiinflammatory activity. The commercial applications of G. procumbens have also been summarized in this paper based on existing patents. The data compiled illustrate that G. procumbens is a potential natural source of compounds with various pharmacological actions which can be utilized for the development of novel therapeutic agents.
publisher Frontiers Media S.A.
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791373/
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