Efficient Gene Knockdown in Mouse Oocytes through Peptide Nanoparticle-Mediated SiRNA Transfection

The use of mouse oocytes as a model for studying female meiosis is very important in reproductive medicine. Gene knockdown by specific small interfering RNA (siRNA) is usually the first step in the study of the function of a target gene in mouse oocytes during in vitro maturation. Traditionally, the...

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Bibliographic Details
Main Authors: Jin, Zhen, Li, Ruichao, Zhou, Chunxiang, Shi, Liya, Zhang, Xiaolan, Yang, Zhixia, Zhang, Dong
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790955/