Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G
Host genomes have adopted several strategies to curb the proliferation of transposable elements and viruses. A recently discovered novel primate defense against retroviral infection involves a single-stranded DNA-editing enzyme, APOBEC3G, that causes hypermutation of HIV. The HIV-encoded virion infe...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Public Library of Science
2004
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC479043/ |