Palmoplantar keratoderma in Slurp2-deficient mice

Palmoplantar keratoderma in Slurp2-deficient mice

SLURP1, a member of the Ly6 protein family, is secreted by suprabasal keratinocytes. Mutations in SLURP1 cause a palmoplantar keratoderma (PPK) known as mal de Meleda. Another secreted Ly6 protein, SLURP2, is encoded by a gene located ~20 kb downstream from SLURP1. SLURP2 is produced by suprabasal k...

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Bibliographic Details
Main Authors: Allan, Christopher M., Procaccia, Shiri, Tran, Deanna, Tu, Yiping, Barnes, Richard H., Larsson, Mikael, Allan, Bernard B., Young, Lorraine C., Hong, Cynthia, Tontonoz, Peter, Fong, Loren G., Young, Stephen G., Beigneux, Anne P.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789766/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789766/

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