Identification of novel RNA secondary structures within the hepatitis C virus genome reveals a cooperative involvement in genome packaging

Identification of novel RNA secondary structures within the hepatitis C virus genome reveals a cooperative involvement in genome packaging

The specific packaging of the hepatitis C virus (HCV) genome is hypothesised to be driven by Core-RNA interactions. To identify the regions of the viral genome involved in this process, we used SELEX (systematic evolution of ligands by exponential enrichment) to identify RNA aptamers which bind spec...

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Bibliographic Details
Main Authors: Stewart, H., Bingham, R.J., White, S. J., Dykeman, E. C., Zothner, C., Tuplin, A. K., Stockley, P. G., Twarock, R., Harris, M.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789732/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789732/

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