Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease

Real-time quaking-induced conversion (RT-QuIC) allows the amplification of miniscule amounts of scrapie prion protein (PrPSc). Recent studies applied the RT-QuIC methodology to cerebrospinal fluid (CSF) for diagnosing human prion diseases. However, to date, there has not been a formal multi-centre a...

Full description

Bibliographic Details
Main Authors: Cramm, Maria, Schmitz, Matthias, Karch, André, Mitrova, Eva, Kuhn, Franziska, Schroeder, Bjoern, Raeber, Alex, Varges, Daniela, Kim, Yong-Sun, Satoh, Katsuya, Collins, Steven, Zerr, Inga
Format: Online
Language:English
Published: Springer US 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789202/