Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease
Real-time quaking-induced conversion (RT-QuIC) allows the amplification of miniscule amounts of scrapie prion protein (PrPSc). Recent studies applied the RT-QuIC methodology to cerebrospinal fluid (CSF) for diagnosing human prion diseases. However, to date, there has not been a formal multi-centre a...
Main Authors: | , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Springer US
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789202/ |