An overview of heavy-atom derivatization of protein crystals

This review summarizes the reasons why the heavy-atom derivatization of protein crystals can be useful, how to select heavy atoms, how to produce a heavy-atom-modified crystal that still diffracts and how to determine whether the protein has been modified.

Bibliographic Details
Main Authors: Pike, Ashley C. W., Garman, Elspeth F., Krojer, Tobias, von Delft, Frank, Carpenter, Elisabeth P.
Format: Online
Language:English
Published: International Union of Crystallography 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784662/