Therapeutic Effect of Losartan, an Angiotensin II Type 1 Receptor Antagonist, on CCl4-Induced Skeletal Muscle Injury

TGF-β1 is known to inhibit muscle regeneration after muscle injury. However, it is unknown if high systemic levels of TGF-β can affect the muscle regeneration process. In the present study, we demonstrated the effect of a CCl4 intra-peritoneal injection and losartan (an angiotensin II type 1 recepto...

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Bibliographic Details
Main Authors: Hwang, Ok-Kyung, Park, Jin-Kyu, Lee, Eun-Joo, Lee, Eun-Mi, Kim, Ah-Young, Jeong, Kyu-Shik
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783959/