Mismatch detection in DNA monolayers by atomic force microscopy and electrochemical impedance spectroscopy
Background: DNA hybridization is at the basis of most current technologies for genotyping and sequencing, due to the unique properties of DNA base-pairing that guarantee a high grade of selectivity. Nonetheless the presence of single base mismatches or not perfectly matched sequences can affect the...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Beilstein-Institut
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778512/ |