Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosis

Cystic fibrosis (CF) results in inflammation, malabsorption of fats and other nutrients, and obstruction in the gastrointestinal (GI) tract, yet the mechanisms linking these disease manifestations to microbiome composition remain largely unexplored. Here we used metagenomic analysis to systematicall...

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Bibliographic Details
Main Authors: Manor, Ohad, Levy, Roie, Pope, Christopher E., Hayden, Hillary S., Brittnacher, Mitchell J., Carr, Rogan, Radey, Matthew C., Hager, Kyle R., Heltshe, Sonya L., Ramsey, Bonnie W., Miller, Samuel I., Hoffman, Lucas R., Borenstein, Elhanan
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778032/