Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma

Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma

Heterogeneity is a hallmark of glioblastoma with intratumoral heterogeneity contributing to variability in responses and resistance to standard treatments. Promoter methylation status of the DNA repair enzyme O6-methylguanine DNA methyltransferase (MGMT) is the most important clinical biomarker in g...

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Bibliographic Details
Main Authors: Parker, Nicole R., Hudson, Amanda L., Khong, Peter, Parkinson, Jonathon F., Dwight, Trisha, Ikin, Rowan J., Zhu, Ying, Cheng, Zhangkai Jason, Vafaee, Fatemeh, Chen, Jason, Wheeler, Helen R., Howell, Viive M.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778014/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778014/

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