Development of three-dimensional lung multicellular spheroids in air- and liquid-interface culture for the evaluation of anticancer therapeutics

Three-dimensional (3D) lung multicellular spheroids (MCS) in liquid-covered culture (LCC) and air-interface culture (AIC) conditions have both been developed for the evaluation of aerosol anticancer therapeutics in solution and aerosols, respectively. The MCS were formed by seeding lung cancer cells...

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Bibliographic Details
Main Authors: MEENACH, SAMANTHA A., TSORAS, ALEXANDRA N., McGARRY, RONALD C., MANSOUR, HEIDI M., HILT, J. ZACH, ANDERSON, KIMBERLY W.
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777598/