Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells

Serum amyloid A (SAA) is an evolutionary highly conserved acute phase protein that is predominantly secreted by hepatocytes. However, its role in liver injury and fibrogenesis has not been elucidated so far. In this study, we determined the effects of SAA on hepatic stellate cells (HSCs), the main f...

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Bibliographic Details
Main Authors: Siegmund, Sören V., Schlosser, Monika, Schildberg, Frank A., Seki, Ekihiro, De Minicis, Samuele, Uchinami, Hiroshi, Kuntzen, Christian, Knolle, Percy A., Strassburg, Christian P., Schwabe, Robert F.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777566/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777566/

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