Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1
The heat shock response is a universal homeostatic cell autonomous reaction of organisms to cope with adverse environmental conditions. In mammalian cells, this response is mediated by the heat shock transcription factor Hsf1, which is monomeric in unstressed cells and upon activation trimerizes, an...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775227/ |