Genomic approaches for understanding dengue: insights from the virus, vector, and host
The incidence and geographic range of dengue have increased dramatically in recent decades. Climate change, rapid urbanization and increased global travel have facilitated the spread of both efficient mosquito vectors and the four dengue virus serotypes between population centers. At the same time,...
| Main Authors: | , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2016
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774013/ |
| id |
pubmed-4774013 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-47740132016-03-03 Genomic approaches for understanding dengue: insights from the virus, vector, and host Sim, Shuzhen Hibberd, Martin L. Review The incidence and geographic range of dengue have increased dramatically in recent decades. Climate change, rapid urbanization and increased global travel have facilitated the spread of both efficient mosquito vectors and the four dengue virus serotypes between population centers. At the same time, significant advances in genomics approaches have provided insights into host–pathogen interactions, immunogenetics, and viral evolution in both humans and mosquitoes. Here, we review these advances and the innovative treatment and control strategies that they are inspiring. BioMed Central 2016-03-02 /pmc/articles/PMC4774013/ /pubmed/26931545 http://dx.doi.org/10.1186/s13059-016-0907-2 Text en © Sim and Hibberd. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Sim, Shuzhen Hibberd, Martin L. |
| spellingShingle |
Sim, Shuzhen Hibberd, Martin L. Genomic approaches for understanding dengue: insights from the virus, vector, and host |
| author_facet |
Sim, Shuzhen Hibberd, Martin L. |
| author_sort |
Sim, Shuzhen |
| title |
Genomic approaches for understanding dengue: insights from the virus, vector, and host |
| title_short |
Genomic approaches for understanding dengue: insights from the virus, vector, and host |
| title_full |
Genomic approaches for understanding dengue: insights from the virus, vector, and host |
| title_fullStr |
Genomic approaches for understanding dengue: insights from the virus, vector, and host |
| title_full_unstemmed |
Genomic approaches for understanding dengue: insights from the virus, vector, and host |
| title_sort |
genomic approaches for understanding dengue: insights from the virus, vector, and host |
| description |
The incidence and geographic range of dengue have increased dramatically in recent decades. Climate change, rapid urbanization and increased global travel have facilitated the spread of both efficient mosquito vectors and the four dengue virus serotypes between population centers. At the same time, significant advances in genomics approaches have provided insights into host–pathogen interactions, immunogenetics, and viral evolution in both humans and mosquitoes. Here, we review these advances and the innovative treatment and control strategies that they are inspiring. |
| publisher |
BioMed Central |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774013/ |
| _version_ |
1613545943407263744 |