Implementation of new approaches for generating conventional reassortants for live attenuated influenza vaccine based on Russian master donor viruses

Implementation of new approaches for generating conventional reassortants for live attenuated influenza vaccine based on Russian master donor viruses

Cold-adapted influenza strains A/Leningrad/134/17/57 (H2N2) and B/USSR/60/69, originally developed in Russia, have been reliable master donors of attenuation for preparing live attenuated influenza vaccines (LAIV). The classical strategy for generating LAIV reassortants is robust, but has some disad...

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Bibliographic Details
Main Authors: Shcherbik, Svetlana, Pearce, Nicholas, Kiseleva, Irina, Larionova, Natalie, Rudenko, Larisa, Xu, Xiyan, Wentworth, David E., Bousse, Tatiana
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773654/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773654/

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