The synthesis and coupling of photoreactive collagen-based peptides to restore integrin reactivity to an inert substrate, chemically-crosslinked collagen

Collagen is frequently advocated as a scaffold for use in regenerative medicine. Increasing the mechanical stability of a collagen scaffold is widely achieved by cross-linking using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and N-hydroxysuccinimide (NHS). However, this treatment consumes t...

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Bibliographic Details
Main Authors: Malcor, Jean-Daniel, Bax, Daniel, Hamaia, Samir W., Davidenko, Natalia, Best, Serena M., Cameron, Ruth E., Farndale, Richard W., Bihan, Dominique
Format: Online
Language:English
Published: Elsevier Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773407/