Palmitate-induced Regulation of PPARγ via PGC1α: a Mechanism for Lipid Accumulation in the Liver in Nonalcoholic Fatty Liver Disease
The aim was to examine the effect of free fatty acids on the regulation of PPARγ-PGC1α pathway, and the effect of PPARγ/PGC1α in NAFLD. The mRNA and protein expression of PGC1α and phospho/total PPARγ were examined in Huh7 cells after the palmitate/oleate treatment with/without the transfection with...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Ivyspring International Publisher
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773281/ |