Age-Dependent Demethylation of Sod2 Promoter in the Mouse Femoral Artery

We studied the age-dependent regulation of the expression of the antioxidant enzyme manganese superoxide dismutase (MnSOD encoded by Sod2) through promoter methylation. C57Bl/6 mice were either (i) sedentary (SED), (ii) treated with the antioxidant catechin (CAT), or (iii) voluntarily exercised (EX)...

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Bibliographic Details
Main Authors: Nguyen, Albert, Leblond, François, Mamarbachi, Maya, Geoffroy, Steve, Thorin, Eric
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771915/