MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cells

Targeted anticancer therapies represent the most effective pharmacological strategies in terms of clinical responses. In this context, genetic alteration of several oncogenes represents an optimal predictor of response to targeted therapy. Integration of large-scale molecular and pharmacological dat...

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Bibliographic Details
Main Authors: Taccioli, Cristian, Sorrentino, Giovanni, Zannini, Alessandro, Caroli, Jimmy, Beneventano, Domenico, Anderlucci, Laura, Lolli, Marco, Bicciato, Silvio, Del Sal, Giannino
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770742/