BubbleTree: an intuitive visualization to elucidate tumoral aneuploidy and clonality using next generation sequencing data

BubbleTree: an intuitive visualization to elucidate tumoral aneuploidy and clonality using next generation sequencing data

Tumors are characterized by properties of genetic instability, heterogeneity, and significant oligoclonality. Elucidating this intratumoral heterogeneity is challenging but important. In this study, we propose a framework, BubbleTree, to characterize the tumor clonality using next generation sequenc...

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Bibliographic Details
Main Authors: Zhu, Wei, Kuziora, Michael, Creasy, Todd, Lai, Zhongwu, Morehouse, Christopher, Guo, Xiang, Sebastian, Yinong, Shen, Dong, Huang, Jiaqi, Dry, Jonathan R., Xue, Feng, Jiang, Liyan, Yao, Yihong, Higgs, Brandon W.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770205/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770205/

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