PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining

The response to DNA double-strand breaks (DSBs) requires alterations in chromatin structure to promote the assembly of repair complexes on broken chromosomes. Non-homologous end-joining (NHEJ) is the dominant DSB repair pathway in human cells, but our understanding of how it operates in chromatin is...

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Bibliographic Details
Main Authors: Luijsterburg, Martijn S., de Krijger, Inge, Wiegant, Wouter W., Shah, Rashmi G., Smeenk, Godelieve, de Groot, Anton J.L., Pines, Alex, Vertegaal, Alfred C.O., Jacobs, Jacqueline J.L., Shah, Girish M., van Attikum, Haico
Format: Online
Language:English
Published: Cell Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769320/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769320/

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