Alteration of the DNA methylation status of donor cells impairs the developmental competence of porcine cloned embryos

Alteration of the DNA methylation status of donor cells impairs the developmental competence of porcine cloned embryos

Nuclear reprogramming induced by somatic cell nuclear transfer is an inefficient process, and donor cell DNA methylation status is thought to be a major factor affecting cloning efficiency. Here, the role of donor cell DNA methylation status regulated by 5-aza-2'-deoxycytidine (5-aza-dC) or 5-...

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Bibliographic Details
Main Authors: HUAN, Yan Jun, WU, Zhan Feng, ZHANG, Ji Guang, ZHU, Jiang, XIE, Bing Teng, WANG, Jian Yu, LI, Jing Yu, XUE, Bing Hua, KONG, Qing Ran, LIU, Zhong Hua
Format: Online
Language:English
Published: The Society for Reproduction and Development 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768780/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768780/

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