FOXO1 inhibits osteosarcoma oncogenesis via Wnt/β-catenin pathway suppression

Recent advances have highlighted profound roles of FOXO transcription factors, especially FOXO1, in bone development and remodeling. The regulation of bone development by FOXOs seems to be stage-specific or context dependent. FOXOs promote maintenance and differentiation of early progenitors of the...

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Bibliographic Details
Main Authors: Guan, H, Tan, P, Xie, L, Mi, B, Fang, Z, Li, J, Yue, J, Liao, H, Li, F
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767937/