Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis

Grifolin, a secondary metabolite isolated from the fresh fruiting bodies of the mushroom Albatrellus confluens, has been reported by us and others to display potent antitumor effects. However, the molecular target of grifolin has not been identified and the underlying mechanism of action is not full...

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Bibliographic Details
Main Authors: Luo, Xiangjian, Yang, Lifang, Xiao, Lanbo, Xia, Xiaofeng, Dong, Xin, Zhong, Juanfang, Liu, Ying, Li, Namei, Chen, Ling, Li, Hongde, Li, Wei, Liu, Wenbin, Yu, Xinfang, Chen, Hanyong, Tang, Min, Weng, Xinxian, Yi, Wei, Bode, Ann, Dong, Zigang, Liu, Jikai, Cao, Ya
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767464/