Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APCMin/+ Mouse Model of Intestinal Tumorigenesis

Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APCMin/+ Mouse Model of Intestinal Tumorigenesis

Nonsteroidal anti-inflammatory drugs have been shown to reduce the incidence of gastrointestinal cancers, but the propensity of these drugs to cause ulcers and bleeding limits their use. H2S has been shown to be a powerful cytoprotective and anti-inflammatory substance in the digestive system. This...

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Bibliographic Details
Main Authors: Paul-Clark, Mark, Elsheikh, Wagdi, Kirkby, Nicholas, Chan, Melissa, Devchand, Pallavi, Agbor, Terence A., Flannigan, Kyle L., Cheadle, Charlotte, Freydin, Maxim, Ianaro, Angela, Mitchell, Jane A., Wallace, John L.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766010/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766010/

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