Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is a very rare disease that has been investigated for over one century and has revealed unique aspects of the pathogenesis and pathophysiology of a hemolytic anemia. PNH results from expansion of a clone of hematopoietic cells that, as a consequence of an in...

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Bibliographic Details
Main Author: Luzzatto, Lucio
Format: Online
Language:English
Published: F1000Research 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765720/