Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model

Background. Diabetic kidney disease is the leading cause of end-stage renal failure despite intensive treatment of modifiable risk factors. Identification of new drug targets is therefore of paramount importance. The complement system is emerging as a potential new target. The lectin pathway of the...

Full description

Bibliographic Details
Main Authors: Østergaard, Jakob Appel, Ruseva, Marieta Milkova, Malik, Talat Habib, Hoffmann-Petersen, Ingeborg Torp, Pickering, Matthew Caleb, Thiel, Steffen, Hansen, Troels Krarup
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764751/