Multiscale alterations in bone matrix quality increased fragility in steroid induced osteoporosis

A serious adverse clinical effect of glucocorticoid steroid treatment is secondary osteoporosis, enhancing fracture risk in bone. This rapid increase in bone fracture risk is largely independent of bone loss (quantity), and must therefore arise from degradation of the quality of the bone matrix at t...

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Bibliographic Details
Main Authors: Karunaratne, A., Xi, L., Bentley, L., Sykes, D., Boyde, A., Esapa, C.T., Terrill, N.J., Brown, S.D.M., Cox, R.D., Thakker, R.V., Gupta, H.S.
Format: Online
Language:English
Published: Elsevier Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764652/