Whole-genome mutational burden analysis of three pluripotency induction methods

Whole-genome mutational burden analysis of three pluripotency induction methods

There is concern that the stresses of inducing pluripotency may lead to deleterious DNA mutations in induced pluripotent stem cell (iPSC) lines, which would compromise their use for cell therapies. Here we report comparative genomic analysis of nine isogenic iPSC lines generated using three reprogra...

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Bibliographic Details
Main Authors: Bhutani, Kunal, Nazor, Kristopher L., Williams, Roy, Tran, Ha, Dai, Heng, Džakula, Željko, Cho, Edward H., Pang, Andy W. C., Rao, Mahendra, Cao, Han, Schork, Nicholas J., Loring, Jeanne F.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762882/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762882/

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