Transport of pyruvate into mitochondria is involved in methylmercury toxicity

We have previously demonstrated that the overexpression of enzymes involved in the production of pyruvate, enolase 2 (Eno2) and D-lactate dehydrogenase (Dld3) renders yeast highly sensitive to methylmercury and that the promotion of intracellular pyruvate synthesis may be involved in intensifying th...

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Bibliographic Details
Main Authors: Lee, Jin-Yong, Ishida, Yosuke, Takahashi, Tsutomu, Naganuma, Akira, Hwang, Gi-Wook
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761912/