Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex
Aberrant signaling through the Raf/MEK/ERK (ERK/MAPK) pathway causes pathology in a family of neurodevelopmental disorders known as 'RASopathies' and is implicated in autism pathogenesis. Here, we have determined the functions of ERK/MAPK signaling in developing neocortical excitatory neur...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758957/ |