An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts
Cancer is a heterogeneous disease caused by diverse genomic alterations in oncogenes and tumor suppressor genes. Despite recent advances in high-throughput sequencing technologies and development of targeted therapies, novel cancer drug development is limited due to the high attrition rate from clin...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Korean Society for Molecular and Cellular Biology
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757806/ |