An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts

Cancer is a heterogeneous disease caused by diverse genomic alterations in oncogenes and tumor suppressor genes. Despite recent advances in high-throughput sequencing technologies and development of targeted therapies, novel cancer drug development is limited due to the high attrition rate from clin...

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Bibliographic Details
Main Authors: Cho, Sung-Yup, Kang, Wonyoung, Han, Jee Yun, Min, Seoyeon, Kang, Jinjoo, Lee, Ahra, Kwon, Jee Young, Lee, Charles, Park, Hansoo
Format: Online
Language:English
Published: Korean Society for Molecular and Cellular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757806/