Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster

Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster

Nucleosomal DNA is thought to be generally inaccessible to DNA-binding factors, such as micrococcal nuclease (MNase). Here, we digest Drosophila chromatin with high and low concentrations of MNase to reveal two distinct nucleosome types: MNase-sensitive and MNase-resistant. MNase-resistant nucleosom...

Full description

Bibliographic Details
Main Authors: Chereji, Răzvan V., Kan, Tsung-Wai, Grudniewska, Magda K., Romashchenko, Alexander V., Berezikov, Eugene, Zhimulev, Igor F., Guryev, Victor, Morozov, Alexandre V., Moshkin, Yuri M.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756854/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756854/

Similar Items