Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA
SMC5/6 is a highly conserved protein complex related to cohesin and condensin, which are the key components of higher-order chromatin structures. The SMC5/6 complex is essential for proliferation in yeast and is involved in replication fork stability and processing. However, the precise mechanism of...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756808/ |