Wnt11 Gene Therapy with Adeno-associated Virus 9 Improves Recovery from Myocardial Infarction by Modulating the Inflammatory Response

Acute myocardial infarction induces activation of the acute phase response and infiltration of leukocytes to the infarcted area. Moreover, myocardium that is remote from ischemic area also becomes inflamed. Inflammatory reaction clears dead cells and matrix debris, while prolongation or expansion of...

Full description

Bibliographic Details
Main Authors: Morishita, Yoshihiro, Kobayashi, Koichi, Klyachko, Ekaterina, Jujo, Kentaro, Maeda, Kengo, Losordo, Douglas W., Murohara, Toyoaki
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756373/