Small RAB GTPases Regulate Multiple Steps of Mitosis

GTPases of the RAB family are key regulators of multiple steps of membrane trafficking. Several members of the RAB GTPase family have been implicated in mitotic progression. In this review, we will first focus on the function of endosome-associated RAB GTPases reported in early steps of mitosis, spi...

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Main Authors:	Miserey-Lenkei, Stéphanie, Colombo, María I.
Format:	Online
Language:	English
Published:	Frontiers Media S.A. 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756281/

id	pubmed-4756281
recordtype	oai_dc
spelling	pubmed-47562812016-02-26 Small RAB GTPases Regulate Multiple Steps of Mitosis Miserey-Lenkei, Stéphanie Colombo, María I. Cell and Developmental Biology GTPases of the RAB family are key regulators of multiple steps of membrane trafficking. Several members of the RAB GTPase family have been implicated in mitotic progression. In this review, we will first focus on the function of endosome-associated RAB GTPases reported in early steps of mitosis, spindle pole maturation, and during cytokinesis. Second, we will discuss the role of Golgi-associated RAB GTPases at the metaphase/anaphase transition and during cytokinesis. Frontiers Media S.A. 2016-02-17 /pmc/articles/PMC4756281/ /pubmed/26925400 http://dx.doi.org/10.3389/fcell.2016.00002 Text en Copyright © 2016 Miserey-Lenkei and Colombo. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Miserey-Lenkei, Stéphanie Colombo, María I.
spellingShingle	Miserey-Lenkei, Stéphanie Colombo, María I. Small RAB GTPases Regulate Multiple Steps of Mitosis
author_facet	Miserey-Lenkei, Stéphanie Colombo, María I.
author_sort	Miserey-Lenkei, Stéphanie
title	Small RAB GTPases Regulate Multiple Steps of Mitosis
title_short	Small RAB GTPases Regulate Multiple Steps of Mitosis
title_full	Small RAB GTPases Regulate Multiple Steps of Mitosis
title_fullStr	Small RAB GTPases Regulate Multiple Steps of Mitosis
title_full_unstemmed	Small RAB GTPases Regulate Multiple Steps of Mitosis
title_sort	small rab gtpases regulate multiple steps of mitosis
description	GTPases of the RAB family are key regulators of multiple steps of membrane trafficking. Several members of the RAB GTPase family have been implicated in mitotic progression. In this review, we will first focus on the function of endosome-associated RAB GTPases reported in early steps of mitosis, spindle pole maturation, and during cytokinesis. Second, we will discuss the role of Golgi-associated RAB GTPases at the metaphase/anaphase transition and during cytokinesis.
publisher	Frontiers Media S.A.
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756281/
_version_	1613539583158386688

Small RAB GTPases Regulate Multiple Steps of Mitosis

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