The Characteristics Variation of Hepatic Progenitors after TGF-β1-Induced Transition and EGF-Induced Reversion

Profibrogenesis cytokine, transforming growth factor- (TGF-) β1, induces hepatic progenitors experiencing epithelial to mesenchymal transition (EMT) to matrix synthesis cells, even tumor initiating cells. Our previous data found that epidermal growth factor (EGF) blocks and reverses TGF-β1-induced t...

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Bibliographic Details
Main Authors: Wang, Ping, Cong, Min, Liu, Tianhui, Yang, Aiting, Sun, Guangyong, Zhang, Dong, Huang, Jian, Sun, Shujie, Mao, Jia, Ma, Hong, Jia, Jidong, You, Hong
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756202/